FDA clears single test for 12 respiratory viruses

first_imgEditor’s note: This story was revised Jan 8 to correct information about the location of the test’s manufacturer. Jan 7, 2008 (CIDRAP News) – A single test that can identify up to 12 different respiratory viruses, including three kinds of influenza, from one sample has won the Food and Drug Administration’s (FDA’s) approval.The test, called the xTAG Respiratory Viral Panel (RVP), is the first that can detect and distinguish influenza A subtypes H1 and H3 and also detect influenza B, the FDA said in announcing the approval on Jan 3. Influenza A is the most severe type of flu in humans and has been the cause of pandemics, the agency noted.The new test panel is also the first test for human metapneumovirus (hMPV), which was first identified in 2001, the FDA said.The test is made by Toronto-based Luminex Molecular Diagnostics, part of Luminex Corp, headquartered in Austin, Tex. In a news release, the company called the xTAG RVP “a ground breaking test that, with a single patient sample, can assess the presence or absence of 12 viral targets and provide qualitative results in a few hours.”Conventional testing for the same viruses requires a number of separate tests and can take several days, the company said. The new product will help physicians provide appropriate treatment and prevent inappropriate antibiotic use that has helped spawn resistant microbes, the statement said.The FDA said, “The xTAG panel is the first FDA-cleared test for infectious respiratory disease viruses that uses a multiplex platform, allowing several tests to be processed using the same sample.”The test uses polymerase chain reaction (PCR) to amplify viral genetic material in samples from patients, according to Jeremy Bridge-Cook, vice president of Luminex Molecular Diagnostics. The FDA said the test uses secretions from the back of the throat.The test uses tiny color-coded beads, or microspheres, that are coated with reagents specific to material from particular viruses, according to information on the Luminex Web site.”There’s a different color-coded bead for each virus in the test,” Bridge-Cook told CIDRAP News. “The Luminex instrument can identify the different color-coded beads and whether the viral target was amplified. If any of the beads is positive, that indicates whether the viral target was present in the sample.”The use of PCR to reproduce viral material “speeds up the usual process of detecting and identifying respiratory viruses, which can take up to a week,” Daniel D. Schultz, MD, director of the FDA’s Center for Devices and Radiological Health, said in the news release.The FDA said viruses identified by the xTAG RVP, in addition to the three forms of influenza and human metapneumovirus, include:Respiratory syncytial virus subtypes A and B, both of which are leading causes of infant pneumonia and bronchiolitis and often contribute to the development of long-term lung diseaseParainfluenza 1, 2, and 3—all leading factors in croup and the common coldRhinovirus, the most common viral infective agent in humans and another cause of the common coldAdenovirus, a cause of respiratory tract infections often similar to strep throat or tonsillitisThe 12 viruses covered by the test account for more than 85% of respiratory viral infections, the Luminex statement said.The company said the test’s ability to identify influenza subtypes H1 and H3 will be important in efforts to detect quickly any emerging pandemic flu virus. The test will make it possible to sort H1 and H3 viruses, which make up the vast majority of influenza A subtypes, from rare forms of influenza A. “This way, the few samples that do test positive for influenza A but cannot be identified as H1 or H3 subtypes can be flagged for further investigation by the CDC or local public health labs,” the company said.Bridge-Cook said the time needed to run the test will vary, but “I’d say maybe 6 hours might be a typical time.”As for the cost, he said he couldn’t give a specific figure, but added, “From a ballpark standpoint, basically the number is in the low hundreds [of dollars], as opposed to thousands of dollars, with respect to what it costs the healthcare system as a whole when the test is run.”Bridge-Cook said the test requires specially trained personnel, so it’s likely to be used mainly in hospital laboratories. But he said many hospital labs take samples from outpatient clinics, so the test would not be limited to use on inpatients.The FDA said that because the test is specific to the 12 viruses listed, it should be used with other diagnostic information, such as patient data, bacterial or viral cultures, and x-rays.See also: Jan 3 FDA news releasehttp://www.fda.gov/bbs/topics/NEWS/2008/NEW01770.htmlJan 3 Luminex news releasehttp://phx.corporate-ir.net/phoenix.zhtml?c=79403&p=irol-newsArticle&ID=1091216&highlight=last_img read more

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ESG roundup: Another investor culls tobacco firms

first_imgSwedish pension and insurance company Länsförsäkringar has divested from all tobacco producers, citing negative health, social and environmental impacts.The company said that tobacco firms had become an increasingly poor investment choice over recent years, but also often disregarded workers’ rights and impacted the environment negatively.Christina Kusoffsky, head of sustainability at Länsförsäkringar, said: “Many may think more about the health problems, but tobacco producers also threaten the environment and biodiversity.“Two thirds of the world’s tobacco is grown in emerging markets. An estimated 200,000 hectares of forest, primarily rainforest, are harvested every year for the benefit of tobacco cultivation and for drying the leaves.” The tobacco cull applies to Länsförsäkringar’s direct investments and its own funds, and includes companies such as Imperial Tobacco Group, Swedish Match and Philip Morris International.The company has also excluded mining company Vale from its investment universe, in the wake of a fatal Brazilian dam collapse in January.Länsförsäkringar said Vale was considered to be among the top 100 greenhouse gas emitters in the world, and also claimed that it had violated human rights conventions.In addition, questions about the condition of other dams controlled by Vale remained unanswered by the company, the Swedish group said.Energy firms review climate lobbying after investor pressure Credit: RWEA coal-fired power plant run by RWE in Westfalen, GermanyAP7 has hailed a “big success” for collaborative efforts with other shareholders in two German companies after they pledged to address concerns about industry lobby groups and climate change.German energy company RWE and German chemicals firm BASF have pledged to put higher demands on the industry groups to which they belong.AP7 – one of Sweden’s largest pension funds – said: “An important key to achieving this success was that several European institutional owners collaborated, not least the German firm Union Investment, which pushed the issue during the general meetings of RWE and BASF.”The pension fund said it had moved its focus to Europe, after driving demand for greater transparency around lobbying in the US for a number of years.AP7 said it had also received an agreement from Germany’s HeidelbergCement, stating that it would review its climate lobbying.Other companies now working to increase the transparency of their lobbying activities include mining companies BHP, Anglo American and Rio Tinto, and oil giant Shell, the fund said.AP7 acknowledged that it would be easier for an institutional investor to avoid such companies by simply selling shares, but emphasised that it was more important to influence them in the right direction instead.last_img read more

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Former Liverpool legend turned Brisbane Roar coach Robbie Fowler is scoring goals in the property market

first_img Justin Bieber’s epic $13m mansion for sale Brisbane Roar new head coach Robbie Fowlera. (Photo by Chris Hyde/Getty Images)Anything from apartments to small houses and large properties that had high rental demand were his favoured list of properties — both in his hometown Liverpool and offshore — and his investments began early during his career.The legendary player, who’s admitted that his property investments came off heeding good advice from financial planners, turned that experience into the Robbie Fowler Property Academy. Liverpool’s Robbie Fowler playing for Liverpool in 1996. Soccer A/CT“It’s not something I do all the time. My wife deals with it. I’m involved with a company who basically teach people (how to buy property),” he told The Courier-Mail.With the family now Queensland-based, his firm has joined forces with Educators Legacy Education Alliance teaching Aussies how to get stuck into real estate via workshops in Brisbane and Melbourne. Basically how “investing in property can give you the chance to earn money in your sleep”, according to Fowler’s own marketing.“Not everything’s going to be positive for everyone, people might think it’s not for them. For me it was a learning curve and you know I learnt so much myself on these courses,” he told the paper.The soccer legend penned his experiences in a new book, My Life In Football, which is set for release November 14.“Hear my thoughts on the modern game, sharing stories from the dressing room, no nailing any players) my legendary teammates as well as my rise to football’s top table,” is how he’s been spruiking it.“It’s coming out November,” he said, “I’ve had one before and it’s probably a little bit of a follow on, talking about all the stuff that’s happened since I created the first (book). I’m looking forward to it actually. It will be good.” Head Coach Robbie Fowler poses during the Brisbane Roar Media Day at the BRFC City of Logan Training Facility on October 02, 2019 in Brisbane, Australia. (Photo by Chris Hyde/Getty Images)Fowler, whose feats include 183 goals in 369 matches for English Premier League giants Liverpool, advises anyone wanting to follow his footsteps in the property market to know where they stand and why they are doing it.What he has dropped off his investment list is race horses.“Funny enough I lost interest when I came over here back in the day (in 2009 to play for North Queensland Fury). I was a jumps man, I prefer the jumps. When I came over to it was more flat, so by the time I went back home I sort of lost interest because it was different horses … I have had a few good horses, various good horses but football made me end it.”His love of property though continues unabated, and his tips for real estate punters were pretty straight forward. Robbie Fowler’s top tips for scoring in the property market “Write down what you want a potential property portfolio to deliver in the short to medium term.” 6. Know the reason why 1. Know your expenses “Check your current score and look into how you can improve your score, if need be,” he said. 4. Know what you want Buyers missing out despite record low rates “Consider whether you want ‘cash flow’ or ‘capital growth’ when considering a property investment career, albeit part or full-time.” 5. Set property goals “Understand the difference between an asset and a liability. Get some professional property training.” 3. Know your credit score Video Player is loading.Play VideoPlayNext playlist itemMuteCurrent Time 0:00/Duration 0:29Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:29 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedQuality Levels720p720pHD540p540p360p360p270p270pAutoA, selectedAudio Tracken (Main), selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.This is a modal window. This modal can be closed by pressing the Escape key or activating the close button.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.PlayMuteCurrent Time 0:00/Duration 0:00Loaded: 0%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -0:00 Playback Rate1xFullscreenWays to get into the property market for less00:29New Brisbane Roar A-League soccer coach, Robbie Fowler — dubbed “God” during his heyday in Liverpool -may be worth an estimated $56 million with as many as 80 properties, but by his own admission, he’s done so by being risk averse.Fowler, who was such a prolific property investor that Manchester City fans changed the words to Yellow Submarine to ‘we all live in a Robbie Fowler house”, has continued his interest in real estate here. MORE NEWS: The House Rules home given a $200k overhaul “When it comes to property investing, first, you need to look at your outgoings and understand where your money is being spent,” he told The Courier-Mail.More from newsParks and wildlife the new lust-haves post coronavirus11 hours agoNoosa’s best beachfront penthouse is about to hit the market11 hours ago“Many people think that owning a home is an asset but if you are mortgaged up to the hilt, this could be seen as more of a liability. So create a monthly outgoings spreadsheet.” 2. Know balance sheets “Put some thought into your ‘why’,” he said. “Is it to spend more time with your family? Or perhaps to pursue your dream of travelling the world? Your why is an intrinsic part of your investing journey. It is a key motivator and reality checker.” *ADDITIONAL REPORTING BY MARCO MONTEVERDElast_img read more

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Heisler: Lakers should add a year to Luke Walton’s contract every time LaVar Ball rips him

first_img Lakers coach Luke Walton believes his job remains safe Kyle Kuzma defends Luke Walton, says most Lakers ‘love playing for him’ Spurs’ Gregg Popovich latest to come to defense of Lakers’ Luke Walton Actually, it was Lonzo’s play and LaVar’s inspiration. Or LaVar’s inspiration and Lonzo’s play. Just ask LaVar.Not that it’s easy … or possible … to deal with someone not even Magic Johnson can charm or persuade. The Lakers had him in on Nov. 29, at which time LaVar said he’d come to them with any complaints.Or that’s what the Lakers thought he said. LaVar’s version, to ESPN’s Ramona Shelburne was, “I am going to say, to plant a seed, ‘Let’s look for this now.’ They might not want to hear that, but it’s going to be successful if you listen to what I’m saying on the fact that I know what it takes for my son to run like this.”If LaVar doesn’t deserve the respect they have shown him, there’s no embarrassing or intimidating him, either, when all he has to do in reply is talk into a live microphone.The Lakers, who know something about stars, had Kobe Bryant, the brashest of the brash, who asked Coach Del Harris as an 18-year-old rookie why they couldn’t run post-ups for him, leaving Delmer to explain they had Shaquille O’Neal for that.Anguished as Kobe was at not playing more than 16 minutes a game in his first season, his father, Joe, a former NBA player who was at every game, never uttered a peep.I knew Joe from Philadelphia, where I covered him as a young player. In Los Angeles he declined to do interviews for years, saying this was Kobe’s time.Suggesting how secure Walton feels, he joked about lifting Lonzo in the win over Atlanta because “his father was talking (trash).”Showing how big this story has gotten, you can now buy “DNP, Coach’s Decision (Dad was talking (trash)” T-shirts online for $25 – which is pricey, but half the price of the cheapest tee on the Big Baller Brand site.Big Baller, of course, is a hype-driven shell company with no advertising budget, the Better Business Bureau citing it for not fulfilling orders and the apparel company that made its products suing for non-payment.This BBB hype is nothing compared to LaVar’s boast that he took LiAngelo and LaMelo to Lithuania so both could get to the Lakers by 2020.Believe this: The Lakers will never have more than one Ball on their roster – if that many, assuming they can make a go of it with Lonzo.We’re not talking about Pau and Marc Gasol. LiAngelo, 19, isn’t considered an NBA prospect. LaMelo is highly regarded for his age – 16 – but a long way away at a listed 6-foot-3, 160 pounds.If a village of 10,000 in Lithuania in winter time with seven hours of daylight isn’t as comfortable for the kids as Westwood or Chino Hills, it’s perfect for LaVar, with the locals changing the team’s schedule for a tournament with the BBB logo plastered everywhere – including the referees’ jerseys – and a female TV reporter asking out Gelo at the introductory press conference.And the press! There was all sorts of press, even if NBA coaches blamed ESPN – unfairly – for LaVar’s nonsense. Detroit’s Stan Van Gundy proposed a boycott of the network. More entertainingly, San Antonio’s Gregg Popovich settled for noting that LaVar is “just another fan from the peanut gallery.”Related Articles Newsroom GuidelinesNews TipsContact UsReport an Error AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREUCLA alum Kenny Clark signs four-year contract extension with PackersIronically, and dismayingly for the Lakers, they’re committed to Walton with Jeanie Buss tweeting #InLukeWeTrust in her New Year’s greeting … but with the heat on, no one had his back.Furious though the Lakers were, they were afraid to reply and make the story even bigger. Luke was left to fend for himself at a tender moment with a nine-game losing streak, including the 37-point home loss to OKC that followed LaVar’s rip, in which Kyle Kuzma said, “We gave up.”Worse was Lonzo’s response – “I can play for anyone” – or was it just low-key Lonzo being Lonzo?Wait a year or two to see if Luke’s still here.In the nick of time, the Lakers won three in a row … whether or not the credit goes to the Luke and the players.center_img Clippers coach Doc Rivers says criticism of Lakers counterpart Luke Walton is ‘awful’ Yes, Daddy Dearest.There’s no getting away from LaVar Ball even when he’s half a world away, continuing his outrages from Lakerdom to Lithuania.The Lakers live for the day they no longer hear his name, but there’s no pretending he doesn’t exist – as they’re trying to do – or that his latest rip of Luke Walton wasn’t a distraction, or that it’s not damaging their brand as they prepare to pursue elite free agents.In the annals of problem parents, this is beyond the Marv Marinoviches. LaVar is more like Faye Dunaway playing Joan Crawford in the 1981 film, using her children as extras, ordering them to call her “Mommy Dearest” and visiting her hysteria on them as her movie queen status fades. Lonzo Ball says he’ll ‘play for anybody’ after LaVar blasts Lakers coach Luke Walton Unfortunately for the Lakers, they find themselves buffetted on all sides at a time their brand is all-important for impressing LeBron James, Paul George et al. Players are aware that all but three or four of them could be outward-bound and morale is already on a precipice.What to do the next time they lose two in a row and LaVar sees guys aren’t high-fiving each other coming out of the game?The Lakers can 1) say nothing and let Walton dangle, which is bad; or 2) give Luke a vote of confidence, a well-known red flag for trouble, which is worse.Or maybe No. 2 is bad and No. 1 is worse.I’ve got it: Every time LaVar rips Walton, add a year to Luke’s contract. For a team making more than $100 million per year in local TV revenue, another year of Luke’s $5 million salary is chump change if it sticks a cork in LaVar.last_img read more

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Lakers’ Kyle Kuzma keeps churning through busy summer at Team USA camp

first_img Newsroom GuidelinesNews TipsContact UsReport an Error Lakers, Clippers schedules set for first round of NBA playoffs AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREUCLA alum Kenny Clark signs four-year contract extension with PackersAs Davis, the Lakers’ new star, works to ingrain himself into his new team and town, Kuzma, 24, has his eyes firmly set on a trip to China this summer for the FIBA World Cup. The roster practicing in Las Vegas this week under coach Gregg Popovich is characterized by who’s missing as much as who is available: Davis, James Harden, Bradley Beal, DeMar DeRozan and Kevin Love are among the players who declined invitations to play this summer. Kemba Walker, Khris Middleton and Kyle Lowry are the only 2019 All-Stars who are attending a camp typically defined by headliner talent.It’s surely a bit demanding: The 40-day experience will call for a trek through Southern California, Australia and eventually China, where a relatively untested group will be thrown in with the best competition international basketball can offer. Kuzma, who has gone from a fringe roster candidate to a near lock to make the final cut, is fully bought in.“At the end of the day, I love playing basketball,” he said. “Can’t take it for granted. When I’m 37, 38, I would look back and ask, ‘Why didn’t I play FIBA when I was 24?’ I want to live with no regrets.”Kuzma generally has few. But one thing he wished he hadn’t done last season was take too long off. This offseason has been a blur: Kuzma already has visited China this summer, on behalf of Nike and working on other business ventures. Beyond appearances at Summer League alongside Davis and LeBron James, he also headed up another year of his summer camp in Michigan, and has generally been jet-setting since April.Donovan Mitchell, another Team USA roster hopeful and a close friend, says Kuzma’s stacked schedule is something he admires. They take cues from each other: When Kuzma hired a personal chef, Mitchell decided he needed one, too. He saw Kuzma working out immediately after he came back from overseas last time, and it inspired Mitchell to jump back onto the court after he did some traveling himself, he said. Trail Blazers beat Grizzlies in play-in, earn first-round series with the Lakers Lakers practice early hoping to answer all questions How athletes protesting the national anthem has evolved over 17 years center_img Trail Blazers, Grizzlies advance to NBA play-in game; Suns, Spurs see playoff dreams dashed “We push each other to be better,” he said. “That relationship allows us to push each other in different ways. Not a lot of friends do that.”Team USA could be a watershed moment for not only Kuzma, but for the 2017 draft class. Boston’s Jayson Tatum, Sacramento’s De’Aaron Fox and Miami’s Bam Adebayo are also among the players in camp this week, seizing advantage of the stars’ absences.Related Articles LAS VEGAS – Though they’re all wearing the same jersey for the next few weeks, Kyle Kuzma has only started getting used to being surrounded by enemies.Not enemies per se — just NBA rivals. But it’s a pronounced imbalance: Between the Team USA senior men’s national team and the Select Team roster, the Celtics, Kings, Nets, Bucks, Nuggets and Hawks are among the teams with multiple players on the court at UNLV during training camp.As the only Lakers representative, he can feel a little outnumbered.“It’s lonely,” he said, with a hint of tongue-in-cheek. “My boy [Anthony Davis] was supposed to come, but he’s got other plans.” Kuzma said he thinks his all-around game has developed over the summer since the Lakers ended their season in April. Video clips of his improved shooting stroke have circulated online, and it could be a moment for him to showcase improved perimeter offense that he’s expected to bring next year.“Keeping it high, using my wrists and be strong flicking it, use my legs,” he said. “I don’t want to be overthinking it. Just those three things, and trust the process.”The early days of camp have helped Kuzma and the rest of his Team USA mates break down their NBA rivalries. He said over time, he expects to “smash” some of the walls between his regular season foes.But he’s taking notes as well: “You kind of get the tendencies for guys and what they wanna do. You see how a lot of that plays into guys getting recruited to play with each other, or scouting teams come playoff time.”last_img read more

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